Christophe Verlinde: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

1

Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection

Cho Yeow Koh, Jessica E. Kim, Sayaka Shibata, Ranae M. Ranade, Mingyan Yu, Jiyun Liu, J. Robert Gillespie, Frederick S. Buckner, Christophe L.M.J. Verlinde, Erkang Fan, Wim G.J. Hol

Journal:

Year:

2012

Language:

english

File:

PDF, 5.12 MB

english, 2012

2

Simplified YM-26734 inhibitors of secreted phospholipase A2 group IIA

Rob C. Oslund, Nathan Cermak, Christophe L.M.J. Verlinde, Michael H. Gelb

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 261 KB

english, 2008

3

Anchor-Based Design of Improved Cholera Toxin and E. coli Heat-Labile Enterotoxin Receptor Binding Antagonists that Display Multiple Binding Modes

Jason C. Pickens, Ethan A. Merritt, Misol Ahn, Christophe L.M.J. Verlinde, Wim G.J. Hol, Erkang Fan

Journal:

Chemistry & Biology

Year:

2002

Language:

english

File:

PDF, 293 KB

english, 2002

4

Cloning and analysis of Trypanosoma cruzi lanosterol 14α-demethylase

Frederick S Buckner, Bridget M Joubert, Sean M Boyle, Richard T Eastman, Christophe L.M.J Verlinde, Seiichi P.T Matsuda

Journal:

Molecular and Biochemical Parasitology

Year:

2003

Language:

english

File:

PDF, 158 KB

english, 2003

5

Resistance mutations at the lipid substrate binding site of Plasmodium falciparum protein farnesyltransferase

Richard T. Eastman, John White, Oliver Hucke, Kohei Yokoyama, Christophe L.M.J. Verlinde, Michael A. Hast, Lorena S. Beese, Michael H. Gelb, Pradipsinh K. Rathod, Wesley C. Van Voorhis

Journal:

Molecular and Biochemical Parasitology

Year:

2007

Language:

english

File:

PDF, 313 KB

english, 2007

6

AB5 toxins: structures and inhibitor design

Erkang Fan, Ethan A Merritt, Christophe LMJ Verlinde, Wim GJ Hol

Journal:

Current Opinion in Structural Biology

Year:

2000

Language:

english

File:

PDF, 652 KB

english, 2000

7

Conformational changes in Leishmania mexicana glyceraldehyde-3-phosphate dehydrogenase induced by designed inhibitors

Stephen Suresh, Jerome C Bressi, Kevin J Kennedy, Christophe L.M.J Verlinde, Michael H Gelb, Wim G.J Hol

Journal:

Journal of Molecular Biology

Year:

2001

Language:

english

File:

PDF, 970 KB

english, 2001

8

Crystal Structures of Trypanosomal Histidyl-tRNA Synthetase Illuminate Differences between Eukaryotic and Prokaryotic Homologs

Ethan A. Merritt, Tracy L. Arakaki, J. Robert Gillespie, Eric T. Larson, Angela Kelley, Natascha Mueller, Alberto J. Napuli, Jessica Kim, Li Zhang, Christophe L.M.J. Verlinde, Erkang Fan, Frank Zucker

Journal:

Journal of Molecular Biology

Year:

2010

Language:

english

File:

PDF, 1.85 MB

english, 2010

9

Optimization of methionyl tRNA-synthetase inhibitors for treatment of Cryptosporidium infection

Buckner, Frederick S., Ranade, Ranae M., Gillespie, J. Robert, Shibata, Sayaka, Hulverson, Matthew A., Zhang, Zhongsheng, Huang, Wenlin, Choi, Ryan, Verlinde, Christophe L. M. J., Hol, Wim G. J., Ochi

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2019

Language:

english

File:

PDF, 1.98 MB

english, 2019

10

Nonspanning Bivalent Ligands as Improved Surface Receptor Binding Inhibitors of the Cholera Toxin B Pentamer

Jason C. Pickens, Daniel D. Mitchell, Jiyun Liu, Xiaojian Tan, Zhongsheng Zhang, Christophe L.M.J. Verlinde, Wim G.J. Hol, Erkang Fan

Journal:

Chemistry & Biology

Year:

2004

Language:

english

File:

PDF, 920 KB

english, 2004

11

Multivalent Drug Design and Inhibition of Cholera Toxin by Specific and Transient Protein–Ligand Interactions

Jiyun Liu, Darren Begley, Daniel D. Mitchell, Christophe L. M. J. Verlinde, Gabriele Varani, Erkang Fan

Journal:

Chemical Biology & Drug Design

Year:

2008

Language:

english

File:

PDF, 537 KB

english, 2008

12

High-Affinity Pentavalent Ligands of Escherichia coli Heat-Labile Enterotoxin by Modular Structure-Based Design

Fan, Erkang, Zhang, Zhongsheng, Minke, Wendy E., Hou, Zheng, Verlinde, Christophe L. M. J., Hol, Wim G. J.

Journal:

Journal of the American Chemical Society

Year:

2000

Language:

english

File:

PDF, 46 KB

english, 2000

13

2-Oxotetrahydroquinoline-Based Antimalarials with High Potency and Metabolic Stability

Bulbule, Vivek J., Rivas, Kasey, Verlinde, Christophe L. M. J., Van Voorhis, Wesley C., Gelb, Michael H.

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 360 KB

english, 2008

14

Structure-Based Design of a Macrocyclic Inhibitor for Peptide Deformylase

Hu, Xubo, Nguyen, Kiet T., Verlinde, Christophe L. M. J., Hol, Wim G. J., Pei, Dehua

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 123 KB

english, 2003

15

Glycolysis as a target for the design of new anti-trypanosome drugs

Christophe L.M.J. Verlinde, Véronique Hannaert, Casimir Blonski, Michèle Willson, Jacques J. Périé, Linda A. Fothergill-Gilmore, Fred R. Opperdoes, Michael H. Gelb, Wim G.J. Hol, Paul A.M. Michels

Journal:

Drug Resistance Updates

Year:

2001

Language:

english

File:

PDF, 606 KB

english, 2001

16

Rational Modification of a Candidate Cancer Drug for Use Against Chagas Disease

Kraus, James M., Verlinde, Christophe L. M. J., Karimi, Mandana, Lepesheva, Galina I., Gelb, Michael H., Buckner, Frederick S.

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 458 KB

english, 2009

17

Evaluation of Different Virtual Screening Programs for Docking in a Charged Binding Pocket

Deng, Wei, Verlinde, Christophe L. M. J.

Journal:

Journal of Chemical Information and Modeling

Year:

2008

Language:

english

File:

PDF, 3.07 MB

english, 2008

18

Optimization of a binding fragment targeting the “enlarged methionine pocket” leads to potent Trypanosoma brucei methionyl-tRNA synthetase inhibitors

Huang, Wenlin, Zhang, Zhongsheng, Ranade, Ranae M., Gillespie, J. Robert, Barros-Álvarez, Ximena, Creason, Sharon A., Shibata, Sayaka, Verlinde, Christophe L.M.J., Hol, Wim G.J., Buckner, Frederick S.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2017

Language:

english

File:

PDF, 651 KB

english, 2017

19

Assessment of the κ-opioid activity of a series of 6,7-benzomorphans in the rabbit vas deferens

Christophe Verlinde, Camiel De Ranter

Journal:

European Journal of Pharmacology

Year:

1988

Language:

english

File:

PDF, 333 KB

english, 1988

20

Inhibitors of Methionyl-tRNA Synthetase have potent activity on Giardia intestinalis trophozoites

Ranade, Ranae M., Zhang, Zhongsheng, Gillespie, J. Robert, Shibata, Sayaka, Verlinde, Christophe L. M. J., Fan, Erkang, Hol, Wim G. J., Buckner, Frederick S.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 676 KB

english, 2015

21

Automated decision algorithm applied to a field experiment with multiple research objectives: The DC3 campaign

Hanlon, Christopher J., Small, Arthur A., Bose, Satyajit, Young, George S., Verlinde, Johannes

Journal:

Journal of Geophysical Research Atmospheres

Year:

2014

Language:

english

File:

PDF, 807 KB

english, 2014

22

Potential drug-drug interactions and risk of unplanned hospitalization in older patients with cancer: A survey of the prospective ELCAPA (ELderly CAncer PAtients) cohort

Beinse, Guillaume, Reitter, Delphine, Segaux, Lauriane, Carvahlo-Verlinde, Muriel, Rousseau, Benoit, Tournigand, Christophe, Cudennec, Tristan, Laurent, Marie, Boudou-Rouquette, Pascaline, Paillaud, E

Journal:

Journal of Geriatric Oncology

Year:

2019

Language:

english

File:

PDF, 279 KB

english, 2019

23

Furan revisited: when to avoid ab initio studies on crystal structures

Christophe L. Verlinde, Camiel J. De Ranter

Journal:

Journal of Molecular Structure: THEOCHEM

Year:

1989

Language:

english

File:

PDF, 424 KB

english, 1989

24

Crystal Structure of Glycosomal Glyceraldehyde-3-phosphate Dehydrogenase from Leishmania mexicana: Implications for Structure-Based Drug Design and a New Position for the Inorganic Phosphate Binding Site

Kim, Hidong, Feil, Ingeborg K., Verlinde, Christophe L. M. J., Petra, Philip H., Hol, Wim G. J.

Journal:

Year:

1995

Language:

english

File:

PDF, 2.63 MB

english, 1995

25

Structure determination of glycogen synthase kinase-3 from Leishmania major and comparative inhibitor structure–activity relationships with Trypanosoma brucei GSK-3

Kayode K. Ojo, Tracy L. Arakaki, Alberto J. Napuli, Krishna K. Inampudi, Katelyn R. Keyloun, Li Zhang, Wim G.J. Hol, Christophe L.M.J. Verlinde, Ethan A. Merritt, Wesley C. Van Voorhis

Journal:

Molecular and Biochemical Parasitology

Year:

2011

Language:

english

File:

PDF, 1.18 MB

english, 2011

26

Fragment-Based Cocktail Crystallography by the Medical Structural Genomics of Pathogenic Protozoa Consortium

Verlinde, Christophe, Fan, Erkang, Shibata, Sayaka, Zhang, Zhongsheng, Sun, Zhihua, Deng, Wei, Ross, Jennifer, Kim, Jessica, Xiao, Liren, Arakaki, Tracy, Bosch, Jurgen, Caruthers, Jonathan, Larson, Er

Journal:

Current Topics in Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 569 KB

english, 2009

27

An internal sequence targets Trypanosoma brucei triosephosphate isomerase to glycosomes

Nathalie Galland, Stéphane de Walque, Frank G.J. Voncken, Christophe L.M.J. Verlinde, Paul A.M. Michels

Journal:

Molecular and Biochemical Parasitology

Year:

2010

Language:

english

File:

PDF, 1009 KB

english, 2010

28

The structure of tryptophanyl-tRNA synthetase from Giardia lamblia reveals divergence from eukaryotic homologs

Tracy L. Arakaki, Megan Carter, Alberto J. Napuli, Christophe L.M.J. Verlinde, Erkang Fan, Frank Zucker, Frederick S. Buckner, Wesley C. Van Voorhis, Wim G.J. Hol, Ethan A. Merritt

Journal:

Journal of Structural Biology

Year:

2010

Language:

english

File:

PDF, 597 KB

english, 2010

29

Leishmania donovani tyrosyl-tRNA synthetase structure in complex with a tyrosyl adenylate analog and comparisons with human and protozoan counterparts

Barros-Álvarez, Ximena, Kerchner, Keshia M., Koh, Cho Yeow, Turley, Stewart, Pardon, Els, Steyaert, Jan, Ranade, Ranae M., Gillespie, J. Robert, Zhang, Zhongsheng, Verlinde, Christophe L.M.J., Fan, Er

Journal:

Year:

2017

Language:

english

File:

PDF, 5.09 MB

english, 2017

30

The Role of Waters in Docking Strategies with Incremental Flexibility for Carbohydrate Derivatives: Heat-Labile Enterotoxin, a Multivalent Test Case

Minke, Wendy E., Diller, David J., Hol, Wim G. J., Verlinde, Christophe L. M. J.

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 271 KB

english, 1999

31

In-vitro and in-vivo effects of the CYP2C9*11 polymorphism on warfarin metabolism and dose

Tai, Guoying, Farin, Frederico, Rieder, Mark J., Dreisbach, Albert W., Veenstra, David L., Verlinde, Christophe L.M.J., Rettie, Allan E.

Journal:

Pharmacogenetics and Genomics

Year:

2005

Language:

english

File:

PDF, 172 KB

english, 2005

32

Structure of the complex between trypanosomal triosephosphate isomerase and N-hydroxy-4-phosphono-butanamide: Binding at the active site despite an “open” flexible loop conformation

Christophe L.M.J. Verlinde, Cornelis J. Witmans, Tjaard Pijning, Kor H. Kalk, Wim G.J. Hol, Mia Callens, Fred R. Opperdoes

Journal:

Protein Science

Year:

1992

Language:

english

File:

PDF, 711 KB

english, 1992

33

In search of new lead compounds for trypanosomiasis drug design: A protein structure-based linked-fragment approach

Christophe L. M. J. Verlinde, Gabrielle Rudenko, Wim G. J. Hol

Journal:

Journal of Computer-Aided Molecular Design

Year:

1992

Language:

english

File:

PDF, 1.62 MB

english, 1992

34

Structure-based Reevaluation of the Mechanism of Class I Fructose-1,6-bisphosphate Aldolase

Christophe L. M. J. Verlinde, Paulene M. Quigley

Journal:

Journal of Molecular Modeling

Year:

1999

Language:

english

File:

PDF, 172 KB

english, 1999

35

Design and Synthesis of bis -carbamate Analogs of Cyclic bis -(3′-5′)-Diguanylic Acid (c-di-GMP) and the Acyclic Dimer PGPG

Kline, Toni, Jackson, Stona R., Deng, Wei, Verlinde, Christophe L. M. J., Miller, Samuel I.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2008

Language:

english

File:

PDF, 5.29 MB

english, 2008

36

Synthesis and Structure-Activity Relationships of Analogs of 2'-Deoxy-2'-(3-methoxybenzamido)adenosine, a Selective Inhibitor of Trypanosomal Glycosomal Glyceraldehyde-3-phosphate Dehydrogenase

Van Calenbergh, Serge, Verlinde, Christophe L. M. J., Soenens, Johanna, De Bruyn, Andre, Callens, Mia, Blaton, Norbert M., Peeters, Oswald M., Herdewijn, Piet, Rozenski, Jef, Hol, Wim G. J.

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 1.87 MB

english, 1995

37

Selective Tight Binding Inhibitors of Trypanosomal Glyceraldehyde-3-phosphate Dehydrogenase via Structure-Based Drug Design

Aronov, Alex M., Verlinde, Christophe L. M. J., Hol, Wim G. J., Gelb, Michael H.

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 232 KB

english, 1998

38

Urea-Based Inhibitors of Trypanosoma brucei Methionyl-tRNA Synthetase: Selectivity and in Vivo Characterization

Shibata, Sayaka, Gillespie, J. Robert, Ranade, Ranae M., Koh, Cho Yeow, Kim, Jessica E., Laydbak, Joy U., Zucker, Frank H., Hol, Wim G. J., Verlinde, Christophe L. M. J., Buckner, Frederick S., Fan, E

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 2.34 MB

english, 2012

39

2-Oxo-tetrahydro-1,8-naphthyridines as selective inhibitors of malarial protein farnesyltransferase and as anti-malarials

Srinivas Olepu, Praveen Kumar Suryadevara, Kasey Rivas, Kohei Yokoyama, Christophe L.M.J. Verlinde, Debopam Chakrabarti, Wesley C. Van Voorhis, Michael H. Gelb

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 134 KB

english, 2008

40

Protein Heterodimerization through Ligand-Bridged Multivalent Pre-organization: Enhancing Ligand Binding toward Both Protein Targets

Liu, Jiyun, Zhang, Zhongsheng, Tan, Xiaojian, Hol, Wim G. J., Verlinde, Christophe L. M. J., Fan, Erkang

Journal:

Journal of the American Chemical Society

Year:

2005

Language:

english

File:

PDF, 74 KB

english, 2005

41

Modelling weather risk preferences with multi-criteria decision analysis for an aerospace vehicle launch

Caruzzo, Amaury, Belderrain, Mischel Carmen Neyra, Fisch, Gilberto, Young, George S., Hanlon, Christopher J., Verlinde, Johannes

Journal:

Meteorological Applications

Year:

2018

Language:

english

File:

PDF, 2.96 MB

english, 2018

42

Large Cyclic Peptides as Cores of Multivalent Ligands: Application to Inhibitors of Receptor Binding by Cholera Toxin

Zhang, Zhongsheng, Liu, Jiyun, Verlinde, Christophe L. M. J., Hol, Wim G. J., Fan, Erkang

Journal:

Journal of Organic Chemistry

Year:

2004

Language:

english

File:

PDF, 131 KB

english, 2004

43

Structure of Glycosomal Glyceraldehyde-3-Phosphate Dehydrogenase from Trypanosoma brucei Determined from Laue Data

Fred M. D. Vellieux, Janos Hajdu, Christophe L. M. J. Verlinde, Hillie Groendijk, Randy J. Read, Trevor J. Greenhough, John W. Campbell, Kor H. Kalk, Jenny A. Littlechild, Herman C. Watson and Wim G.

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 1.27 MB

english, 1993

44

The calcium-dependent protein kinase 1 from Toxoplasma gondii as target for structure-based drug design

Cardew, Emily M., Verlinde, Christophe L. M. J., Pohl, Ehmke

Journal:

Year:

2017

Language:

english

File:

PDF, 653 KB

english, 2017

45

Structure-Based Design of Submicromolar, Biologically Active Inhibitors of Trypanosomatid Glyceraldehyde-3-Phosphate Dehydrogenase

Alex M. Aronov, Stephen Suresh, Frederick S. Buckner, Wesley C. Van Voorhis, Christophe L. M. J. Verlinde, Fred R. Opperdoes, Wim G. J. Hol and Michael H. Gelb

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.56 MB

english, 1999

46

Adenosine Analogues as Selective Inhibitors of Glyceraldehyde-3-phosphate Dehydrogenase of Trypanosomatidae via Structure-Based Drug Design

Bressi, Jerome C., Verlinde, Christophe L. M. J., Aronov, Alex M., Shaw, My Le, Shin, Sam S., Nguyen, Lisa N., Suresh, Stephen, Buckner, Frederick S., Van Voorhis, Wesley C., Kuntz, Irwin D., Hol, Wim

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 339 KB

english, 2001

47

Protein crystallography and infectious diseases

Christophe L.M.J. Verlinde, Ethan A. Merritt, Focco Van Den Akker, Hidong Kim, Ingeborg Feil, Luis F. Delboni, Shekhar C. Mande, Steve Sarfaty, Philip H. Petra, Wim G.J. Hol

Journal:

Protein Science

Year:

1994

Language:

english

File:

PDF, 10.91 MB

english, 1994

48

Crystal structures of three protozoan homologs of tryptophanyl-tRNA synthetase

Ethan A. Merritt, Tracy L. Arakaki, Robert Gillespie, Alberto J. Napuli, Jessica E. Kim, Frederick S. Buckner, Wesley C. Van Voorhis, Christophe L.M.J. Verlinde, Erkang Fan, Frank Zucker, Wim G.J. Hol

Journal:

Molecular and Biochemical Parasitology

Year:

2011

Language:

english

File:

PDF, 1.26 MB

english, 2011

49

The Protein Farnesyltransferase Inhibitor Tipifarnib as a New Lead for the Development of Drugs against Chagas Disease

Hucke, Oliver, Gelb, Michael H., Verlinde, Christophe L. M. J., Buckner, Frederick S.

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 255 KB

english, 2005

50

Corrections to Rational Modification of a Candidate Cancer Drug for Use against Chagas Disease

Kraus, James M., Verlinde, Christophe L. M. J., Karimi, Mandana, Lepesheva, Galina I., Gelb, Michael H., Buckner, Frederick S.

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 540 KB

english, 2009

To build up a library is to create a life. It’s never just a random collection of books.

— Carlos María Domínguez

Official channel

Z-Library Desktop Launcher

Z-Library Since 2009 support@1delivery.pm

EnglishРусскийEspañolItalianoελληνικάاللغة العربيةBahasa IndonesiaBahasa Malaysiaहिन्दीDeutschFrançaisPortuguêsУкраїнськаPolski中文繁體中文日本語Tiếng ViệtAzərbaycan DiliՀայոց լեզուภาษาไทยTürk Diliქართველიবাংলাپښتوతెలుగుاردو한국어SrpskiБългарски